• Rest for half an hour approximately every 200 kilometers and do arm and leg stretching exercises.
• If you are sleepy, stop to rest for 10 minutes and refresh yourself with cold water, because this promotes stimulation.
• Ventilate the vehicle and avoid smoking, since heat increases sleep by causing a drop in tension, which is a state of greater relaxation.
• Do not drink alcohol; do not eat excessively.
• Avoiding the intake of medicines. If you are on any kind of treatment, check for side effects.
• Wear comfortable clothes.
• At the first symptom of sleepiness, stop in a safe place to sleep for a few minutes and to be able to recover a little.

Source: CEA Foundation